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18001

Eldepryl (Selegiline) 5 mg

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Product info

Commercial Name: Eldepryl
Principal Ingredient: Selegiline
Utilization: Treats Parkinson Syndrome
Available Dosage: 5mg

18001

Product info

Commercial Name: Eldepryl
Principal Ingredient: Selegiline
Utilization: Treats Parkinson Syndrome
Available Dosage: 5mg

  • Product
  • Dosage
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  • Eldepryl
  • 5 mg
  • 30 pills
  • 93.00 €
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  • Eldepryl
  • 5 mg
  • 60 pills
  • 130.00 €
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  • Eldepryl
  • 5 mg
  • 90 pills
  • 168.00 €
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  • Eldepryl
  • 5 mg
  • 120 pills
  • 213.00 €
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ELDEPRYL

Eldepryl is the registered trademark of Somerset Pharmaceuticals Inc. It is used in combination with other drugs to treat Parkinson's disease, Eldepryl is even better known as selegiline, so do not be surprised if you meet one of them or the other name because it is the same medicine.

Eldepryl belongs to the class of drugs called phenethylamines, it is usually used together with other drugs to treat the symptoms of Parkinson's disease. It is also used to treat depression and dementia. Eldepryl may also be used for other purposes not listed in this medication guide.

Why Buy Eldepryl?

This medicine is used to treat disorders caused by Parkinson's disease. It does not cure Parkinson's disease, but it reduces tremors, muscle stiffness, loss of mobility of some members. This medicine can improve your range of motion and the ability to walk, get dressed and exercise certain activities. Selegiline is generally used in combination with other drugs (eg, levodopa, carbidopa). Eldepryl is an enzyme inhibitor (MAO) that works by slowing the breakdown of certain natural substances in the brain (neurotransmitters such as dopamine, norepinephrine and serotonin).

Take this medicine orally, usually twice a day, at breakfast and at lunch. Taking selegiline late in the day can cause sleep disturbances. The dosage is based on your state of health and the reactions to the treatment. Do not change the dosage of the drug, strictly follow the instructions of the doctor because after taking selegiline for 2 or 3 days, your doctor may invite you to gradually reduce the doses of levodopa. The benefits of this drug appear or are felt a few weeks after the start of therapy. Please tell the doctor if the medicine is not producing the expected effects or if your condition is getting worse.

Buy Selegiline Without Prescription – Dosage

Get emergency medical help if you notice any of these signs of the following allergic reaction: hives, difficulty breathing, and swelling of your face, lips, tongue, or throat.
Stop taking selegiline and contact your doctor immediately if you experience any of the following side effects: Sudden and severe headaches, confusion, blurred vision, problems with word articulation during speech, loss of balance, nausea, vomiting, chest pain, sudden numbness and weakness on one side of the body, dizziness, fainting, hallucinations, irritation, muscle contractions, and painful or difficult urination.

Other less serious side effects may include: dizziness, weakness, sleep disorder, runny nose or stuffy nose, low back pain, constipation, mouth sores or ulcers, and swallowing pains.

This list of side effects is not exhaustive and others may occur. Call your doctor for medical advice on any side-effects you may experience.

Possible side effects Eldepryl

Some patients who have received selegiline may experience exacerbation of levodopa, possibly due to increased dopamine responses with highly sensitive postsynaptic receptors. These effects can often be reduced by reducing the levodopa / carbidopa dose by approximately 10 to 30%.

The decision to prescribe selegiline should take into account that the MAO enzyme system is complex and not very well controlled, due to the lack of in-depth laboratory analyzes with selegiline. Therefore, the range of possible responses to selegiline could not be observed during a pre-market evaluation of the drug. Therefore, it is advisable, carefully observe patients, and closely monitor some atypical responses.

Laboratory tests:

No specific laboratory test is considered essential for the management of patients on Eldepryl. A routine routine evaluation of all patients, however, is appropriate. On the other hand, it has been observed in rats and mice during laboratory tests, carcinogenesis, mutagenesis and impairment of the fertility assessment and carcinogenic potential of the drug.
Selegiline did not induce mutations or chromosomal damage in bacterial mutation assays in Salmonella typhimurium and in in vivo chromosomal aberration assays. While these studies reassure that selegiline is not mutagenic or clastogenic, these results are not definitive due to methodological limitations as no definitive in vitro chromosomal aberrations or in vitro mammalian gene mutation assays have been performed.

On the other hand, the effects of selegiline on fertility have not been properly evaluated. In category C pregnancy, no teratogenic effects were observed in an embryo-fetal development study in rats at oral doses of 4, 12 and 36 mg / kg, which represents 4, 12 and 35 times the human therapeutic dose. No teratogenic effects were observed in an embryo-fetal development study in New Zealand white rabbits at oral doses of 5, 25 and 50 mg / kg or 10, 48 and 95 times the human therapeutic dose on a single dose. base mg / m2; However, in this study, the number of litters produced at the two higher doses was less recommended for assessing the teratogenic potential. In the rat study, there was a decrease in body weight of the fetus at the highest dose tested. In the rabbit study, the increase in total resorptions, post-implantation loss, and a decrease in the number of live fetuses per mother occurred at the highest dose tested.

In a peri and postnatal developmental study in Sprague-Dawley rats, an increase in the number of dams born and a decrease in dam numbers, pup survival, and pup body weight (at birth and during the entire lactation period) were observed at two higher doses. At the highest dose tested, no puppies born alive survived the 4th day. Postnatal development at the highest dose tested in the dams could not be assessed due to the lack of small survivors.

There are no adequate and well-controlled studies in pregnant women. Selegiline should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus, but persistent doubts for women who are still breastfeeding with breast milk. It is advisable for them to get closer to specialists to obtain more details.

Eldepryl 5mg Interactions Online

The onset of stupor, muscle rigidity, severe agitation, and elevated temperature have been reported in some patients receiving the combination of selegiline and meperidine. Symptoms usually disappear after a few hours when this combination is not recurrent. This is typical of the interaction of meperidine and MAOIs. Other serious reactions (including severe agitation, hallucinations, and death) have been reported in patients receiving this combination (see contraindications). Severe toxicity has also been reported in patients receiving the combination of tricyclic antidepressants, ELDEPRYL (selegiline hcl) and serotonin reuptake inhibitors. (See warnings for more details.) A case of hypertensive crisis has been reported in a patient taking the recommended doses of selegiline and ephedrine.

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